颅脑MR灌注影像 Cerebral MR Perfusion Imaging pdf snb 115盘 kindle 在线 下载 pmlz mobi

Cerebral hemodynamics - what are they?

How can I use MRI to measure cerebral perfusion in a clinical setting?

What tumors have high blood volume? Can perfusion imaging help define the ischemic penumbra? What should I do if I want to image perfusion in the presence of a leaky BBB?

From the basic principles of perfusion MR imaging to present clinical applications in the assessment of cerebrovascular diseases and intra-cranial tumors this book provides practical information for newcomers to this technique as well as experienced radiologists.

Table of Contents

Preface

Acknowledgements

List of Abbreviations

List of Movie Clips

Part 1: Technical Considerations

Introduction

Cerebral hemodynamics - what are they?

Perfusion MRI with dynamic susceptibility contrast imaging

Why is magnetic susceptibility so powerful?

Why use contrast agents?

Bolus injection versus slow infusion of contrast agent

Why is the status of the BBB important for Perfusion MRI?

How do I image perfusion in the presence of a leaky BBB?

Advantages of available and future contrast agents

What about non-contrast techniques?

Why use rapid imaging techniques?

Should I use spin echo or gradient echo EPI?

What are the detailed typical parameters for perfusion imaging?

Non-EPI Systems

EPI Systems

Can you tell me more about the optimum contrast agent dose?

Do I need a power injector? How do I use it?

How do I perform a manual injection?

Is the injection volume important?

Is field strength important?

How do I postprocess perfusion images?

Overview

Step 0: Before you start

Step 1 : The initial parameter of concentration versus time

Step 2: Analyzing the curve

Step 3: Creating the maps: CBV

Step 4: Creating the maps: CBF

Step 5: Creating the maps: MTT and other timing maps

What advanced techniques may become important in the future?

Compensation for delay and dispersion

Flow heterogeneity

Average vessel diameter

Part 2: Perfusion Imaging in Clinical Practice

Perfusion MRI compared to other routine modalities

Perfusion MRI in cerebrovascular disease

Acute stroke

Stroke pathophysiology and imaging of blood flow

Practical perfusion MRI in acute stroke

Reperfusion

Chronic stroke

Moya-moya

lntraparenchymal hemorrhage

Intracranialtumors

Rationale for perfusion MRI

Diagnosis

Direction of biopsy/intervention

Treatment follow-up

Dementia

Vasospasm

Head trauma

Migraine

Epilepsy

Otherlesions

Conclusion

References

Selected reading

Perfusion methodology

Clinical applications: ischemia

Clinical applications: tumors

Clinical applications: other areas

Non-contrast perfusion methodology

Perfusion MRI in animal studies

Cited papers

Index

CD-ROM Instructions

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